Louisville vs. Indiana: College Football Betting Picks, Predictions and Tips – September 16, 2023

Written By PlayPicks Staff on September 10, 2023

The Louisville Cardinals (2-0) face off against the Indiana Hoosiers (1-1) at Lucas Oil Stadium in Indianapolis, Indiana on September 16, 2023, starting at 12:00 PM ET, airing on BTN. The Cardinals are favored by 10 points in the matchup. The over/under is set at 50.5 in the contest.

Want to bet on Louisville or Indiana in this matchup? Head to DraftKings Sportsbook to place your wager today!

Louisville vs. Indiana Odds

Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds
Louisville -10 -110 -110 50.5 -110 -110

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Computer Pick

Computer picks for Louisville vs Indiana
ATS Total Score prediction
Indiana (+10) Under (50.5) Louisville 28 Indiana 21

Predictions are calculated by a data-driven algorithm (raw power score) that ranks head-to-head matchup results within a closed network of games. Prediction confidence is determined by the delta between each team’s raw power score.

Team Stat Comparison

Louisville Indiana
Off. Points per Game (Rank) 47.5 (21) 22.0 (107)
Def. Points per Game (Rank) 17.0 (36) 15.0 (27)
Turnovers Allowed (Rank) 3 (69) 1 (11)
Turnovers Forced (Rank) 5 (13) 2 (74)

Louisville vs. Indiana Betting Insights

Louisville Stats and Trends

  • Louisville has a record of 1-1-0 against the spread this season.
  • The Cardinals have won their only game this season when playing as at least 10-point favorites.
  • All Louisville games have gone over the point total this season.
  • Louisville has an average point total of 52.5 in their contests this year, 2.0 more points than this matchup’s over/under.

Indiana Stats and Trends

  • Indiana has won all two of its games against the spread this year.
  • The Hoosiers have won their only game this year when playing as at least 10-point underdogs.
  • Games featuring Indiana have gone over the point total once this year.
  • IU’s matchups this season have a 51.8-point average over/under, 1.3 more points than this game’s point total.

Louisville Players to Watch

  • This year, Jack Plummer has put up 494 passing yards (247.0 yards per game) while connecting on 34 of 53 passes (64.2% completion percentage), with four touchdowns and three interceptions. He has tacked on 56 rushing yards on 13 carries, averaging 28.0 yards per game.
  • Jawhar Jordan has rushed for a team-leading 231 yards on 14 attempts (115.5 yards per game) while scoring three touchdowns. He also averages 24.5 receiving yards per game, grabbing three passes for 49 yards.
  • Isaac Guerendo has 90 yards on 17 carries (45.0 ypg), with one rushing touchdown. He also has five catches for 60 yards (30.0 ypg).
  • This season Jamari Thrash has 10 receptions for a team-high 170 receiving yards (85.0 per game) and three touchdowns.
  • Kevin Coleman’s stat line this year shows five catches for 98 yards and one touchdown. He averages 49.0 receiving yards per game.

Indiana Players to Watch

  • Tayven Jackson has thrown for 260 yards while completing 73.1% of his passes (19-of-26).
  • Jaylin Lucas has 21 attempts for a team-high 112 rushing yards (56.0 per game) and two touchdowns. He also has five catches for 40 receiving yards (20.0 per game).
  • Josh Henderson has rushed for 65 yards on 15 carries (32.5 yards per game), with one touchdown on the ground this year. He also has four catches for 58 yards (29.0 per game).
  • Omar Cooper Jr. has racked up seven receptions for 101 yards, best on his team. He averages 101.0 receiving yards per game.
  • Cam Camper has also chipped in with six catches for 72 yards this year. He averages 36.0 receiving yards per game.
  • Donaven McCulley has 64 receiving yards on five receptions, averaging 32.0 yards per game.

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