USC Vs. Notre Dame: College Football Betting Picks, Predictions And Tips – November 26, 2022

Written By PlayPicks Staff on November 22, 2022

The No. 5 USC Trojans (10-1) hit the field against the No. 13 Notre Dame Fighting Irish (8-3) in college football action at Los Angeles Memorial Coliseum in Los Angeles, California. The Fighting Irish (+159 on the moneyline to win) hit the road on November 26, 2022 at 7:30 PM ET on ABC against the Trojans (-4.5). Sportsbooks have listed the matchup’s over/under at 63.5.

The betting trends in this article reference odds valid as of November 26, 2022 at 6:26 PM ET. Head to the table below for the latest lines for this outing and click here to get the best DraftKings Sportsbook deposit bonus!

USC Vs. Notre Dame Odds

Computer Pick

Computer picks for USC vs Notre Dame
Spread Over/Under
USC (-4.5) Under (63.5)

Predictions are calculated by a data-driven algorithm (raw power score) that ranks head-to-head matchup results within a closed network of games. Prediction confidence is determined by the delta between each team’s raw power score.

Team Stat Comparison

USC Stats (Rank) Notre Dame
42.9 (3) Points Per Game 31.0 (49)
26.3 (66) Points Per Game Against 20.3 (26)
330.8 (4) Pass Yards 189.2 (112)
257.8 (105) Pass Yards Against 186.8 (20)
182.2 (45) Rush Yards 191.2 (36)
147.2 (66) Rush Yards Against 130.5 (39)
3 (1) Giveaways 12 (22)
23 (6) Takeaways 13 (87)
+20 Turnover Differential +1

USC Vs. Notre Dame Betting Insights

USC Stats And Trends

  • USC has seven wins in 11 games against the spread this season.
  • This season, USC is 5-4 as 4.5-point or better favorites.
  • There have been eight USC games (of 11) that hit the over this year.
  • Eight times so far this season, the Trojans and their opponent have combined to score more than 63.5 points.
  • Trojans games have had an average of 67.0 points this season, 3.5 points higher than the over/under for this matchup.

Notre Dame Stats And Trends

  • Notre Dame is 6-5-0 against the spread this year.
  • Notre Dame has yet to lose ATS (1-0) as a 4.5-point underdog or greater this season.
  • Of 11 Notre Dame games so far this year, six have hit the over.
  • So far this season, four Fighting Irish games have featured over 63.5 points scored.
  • The over/under for this game is 15.5 points higher than the average scoring total for Fighting Irish games (48.0).

USC Players To Watch

  • Caleb Williams has 3,480 passing yards (316.4 ypg) to lead USC, completing 64.9% of his passes and collecting 33 touchdown passes and three interceptions this season. He’s also chipped in on the ground with 316 rushing yards (28.7 ypg) on 88 carries with seven rushing touchdowns.
  • Travis Dye has carried the ball 145 times for a team-high 884 yards (88.4 per game), with nine touchdowns this year. He’s also tacked on 20 catches for 194 yards (19.4 per game).
  • This season Austin Jones has piled up 73 carries for 455 yards (45.5 per game) and five touchdowns, while also catching 16 passes for 191 yards (19.1 per game) and one touchdown.
  • Jordan Addison’s team-high 765 receiving yards (85.0 yards per game) have come on 51 receptions with eight touchdowns.
  • Tahj Washington has put together a 549-yard season so far (61.0 receiving yards per game) with four touchdowns, hauling in 36 passes.
  • Mario Williams’ 21 grabs have netted him 431 yards (61.6 ypg) and four touchdowns.

Notre Dame Players To Watch

  • Drew Pyne leads Notre Dame with 1,703 passing yards (170.3 ypg) on 141-of-228 passing with 19 touchdowns compared to five interceptions this season. He also adds 119 rushing yards (11.9 ypg) on 42 carries while scoring two touchdowns on the ground.
  • The team’s top rusher, Audric Estime, has carried the ball 136 times for 782 yards (71.1 per game), with 11 touchdowns this year.
  • This season Logan Diggs has racked up 698 yards (69.8 per game) on 140 carries with two touchdowns.
  • Michael Mayer’s 711 receiving yards (64.6 yards per game) lead the team. He has 59 receptions with seven touchdowns.
  • Lorenzo Styles Jr. has collected 306 receiving yards (30.6 yards per game) and one touchdown, reeling in 26 passes this year.
  • Jayden Thomas’ 18 catches have netted him 272 yards (30.2 ypg) and three touchdowns.

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