49ers vs. Steelers Predictions & Best Bets: Spread, Moneyline, Over/Under and Props | Week 1

Written By PlayPicks Staff on September 9, 2023

The Pittsburgh Steelers (0-0) take on the San Francisco 49ers (0-0) at Acrisure Stadium on Sunday, September 10, 2023, and here are our best bets.

Wanting to use DraftKings to make a wager? Signing up is simple. Just get your computer, phone, or mobile device, along with a method of payment for your first deposit. Then follow our link, and the DraftKings site or app will guide you through the sign-up process.

Ready to put your picks to the test? Sign up for DraftKings Sportsbook and bet on this matchup today!

Spread: 49ers (-2) to Cover

  • The DraftKings line for this game has the 49ers favored by two, while the model predicts they’ll win by slightly more (4.6 points).
  • San Francisco went 11-6-0 ATS last season.
  • The 49ers had an ATS record of 12-4 when playing as at least 2-point favorites last season.
  • Pittsburgh covered 10 times in 17 chances against the spread last year.
  • The Steelers were 5-4-1 ATS last season when playing as at least 2-point underdogs.

Think the 49ers will cover? Sign up and bet with DraftKings Sportsbook.

Total: Under 41.5

  • The DraftKings total for this game, 41.5 points, and the model’s projected total, 40.7 points, are only 0.8 points apart.
  • In 11 games last year, San Francisco and its opponent combined to score more than 41.5 points.
  • Last year, six Pittsburgh games featured more than 41.5 points scored.
  • Last season, nine of the 49ers’ games went over the point total.
  • In Steelers games last season, combined scoring went over the point total seven times.

Will this matchup go under the total? Check out DraftKings Sportsbook for the latest odds and to get the best signup offer using our link!

Moneyline Winner: 49ers (-125)

  • Prediction:
    San Francisco 23 – Steelers 18

Which team do you think will end up on top? Sign up for DraftKings Sportsbook and make your pick!

49ers and Steelers Splits

49ers (2022) Steelers (2022)
Record 13-4 9-8
At Home 8-1 4-4
On the Road 5-3 5-4
In Conference 10-2 5-7
In Division 6-0 3-3
One Possession Games 3-1 7-5
Indoor 0-1 2-0
Outdoor 13-3 7-8

Interested in more information about this game? Check out the full preview here!

Not all offers available in all states, please visit DraftKings for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.

PlayPicks Staff Avatar
Written by
PlayPicks Staff

PlayPicks staff has years of sports betting and DFS knowledge and we share all of that with you for free daily.

View all posts by PlayPicks Staff
Privacy Policy