The San Francisco 49ers (0-0) and the Pittsburgh Steelers (0-0) start the 2023 NFL season on Sunday, September 10, with kickoff set for 1:00 PM ET at Acrisure Stadium. The 49ers are coming off a 13-4 season that saw them lose in the NFC Championship Game, while the Steelers went 9-8 last year and missed the playoffs.
The 49ers (-2) are slight favorites against the Steelers. The total is 41.5 points.
The betting trends in the article below use the latest odds as of September 10, 2023 at 11:12 AM ET. Head to the article below for the latest lines for this contest and click here to get the best DraftKings Sportsbook deposit bonus!
49ers Vs Steelers Odds
| Favorite | Spread | Over/Under |
|---|---|---|
| 49ers | -2 | 41.5 |
49ers vs. Steelers Predictions
| ATS pick | Over/Under pick |
|---|---|
| 49ers (-2) | Under (41.5) |
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Team Stat Rankings (2022)
| 49ers | Steelers | |
|---|---|---|
| Off. Points per Game (Rank) | 26.5 (6) | 18.1 (26) |
| Def. Points per Game (Rank) | 16.3 (1) | 20.4 (10) |
| Off. Yards per Play (Rank) | 5.9 (4) | 4.9 (27) |
| Def. Yards per Play (Rank) | 5 (3) | 5.5 (20) |
| Turnovers Allowed (Rank) | 17 (3) | 19 (5) |
| Turnovers Forced (Rank) | 30 (2) | 23 (14) |
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49ers Betting Insights
- The 49ers’ record against the spread last year was 11-6-0.
- As 2-point or greater favorites last season, San Francisco went 12-4.
- Last year, nine of San Francisco’s 17 games went over the point total.
- A total of 11 times last season, the 49ers and their opponent combined for more than 41.5 points.
- The over/under in this matchup is 41.5 points, 0.7 fewer than the average total in last season’s San Francisco contests.
Steelers Betting Insights
- The Steelers’ record against the spread last year was 10-6-1.
- As 2-point underdogs or more, Pittsburgh went 5-4-1 against the spread last year.
- In 17 Steelers games last season, seven of them went over the total.
- Last year, six Pittsburgh games featured over 41.5 points scored.
- Games involving the Steelers last year averaged 40.6 points per game, a 0.9-point differential when compared to the over/under for this contest.
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49ers Players to Watch
- Last year Brock Purdy had 1,374 yards (152.7 per game), a 67.1% completion percentage, 13 touchdowns, and four interceptions.
- Last season Christian McCaffrey churned out 1,139 rushing yards (67 per game) and eight touchdowns. In the receiving game, he made 85 catches for 741 yards and five scores.
- Elijah Mitchell ran for 279 yards on 45 carries (55.8 yards per game), with two rushing touchdowns last year.
- In the previous season, Brandon Aiyuk grabbed 78 passes (on 114 targets) for 1,015 yards (59.7 per game). He also found the end zone eight times.
- George Kittle amassed 765 yards on 60 grabs with 11 touchdowns. He was targeted 86 times, and averaged 51 receiving yards per game.
- Nick Bosa amassed 18.5 sacks, 19 TFL and 51 tackles last season.
- Fred Warner was a wrecking ball on the field, collecting 130 tackles, three TFL, two sacks, and one interception last year.
- Tashaun Gipson intercepted five passes last year while also totaling 61 tackles, one TFL, 0.5 sacks, and eight passes defended.
Steelers Players to Watch
- Kenny Pickett threw for 2,404 yards and seven touchdowns last season. He also chipped in on the ground, accumulating three touchdowns while racking up 237 yards.
- Najee Harris tallied 1,034 rushing yards and seven touchdowns on the ground during last year’s campaign.
- Jaylen Warren rushed for 379 yards and one touchdown last season.
- Diontae Johnson averaged 51.9 receiving yards over the course of the 2022 season.
- George Pickens averaged 47.1 receiving yards on 4.9 targets per game in 2022, scoring four touchdowns.
- Pat Freiermuth hauled in 63 passes on his way to 732 receiving yards and two touchdowns a season ago.
- Last year Alex Highsmith collected 14.5 sacks, 12 TFL and 63 tackles.
- Elandon Roberts was a force on the field last season with 104 tackles, 10 TFL, and 4.5 sacks.
- A year ago Minkah Fitzpatrick collected 96 tackles, one TFL, and 11 passes defended as well as six interceptions.
How to Bet on 49ers vs Steelers
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