The New England Patriots (1-5) and their 31st-ranked scoring offense (12.0 points per game) will need to be firing on all cylinders when they match up with the Buffalo Bills (4-2), who sport the third-ranked scoring defense in the NFL (14.8 points allowed per game). Kickoff is slated for Sunday, October 22 at 1:00 PM ET.
The Patriots are 7.5-point underdogs in their matchup against the Bills (the game has a total of 40 points).
The betting insights in this article reference odds valid as of October 21, 2023 at 7:12 PM ET. Check out the article below for the latest odds for this game and click here to get the best DraftKings Sportsbook deposit bonus!
Bills Vs Patriots Odds
| Favorite | Spread | Over/Under |
|---|---|---|
| Bills | -7.5 | 40 |
Bills vs. Patriots Predictions
| ATS pick | Over/Under pick |
|---|---|
| Bills (-7.5) | Over (40) |
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Team Stat Rankings
| Bills | Patriots | |
|---|---|---|
| Off. Points per Game (Rank) | 28.8 (3) | 12.0 (31) |
| Def. Points per Game (Rank) | 14.8 (5) | 25.3 (24) |
| Off. Yards per Play (Rank) | 6.0 (2) | 4.5 (27) |
| Def. Yards per Play (Rank) | 5.5 (23) | 4.8 (7) |
| Turnovers Allowed (Rank) | 9 (18) | 11 (27) |
| Turnovers Forced (Rank) | 13 (2) | 3 (32) |
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Bills Betting Insights
- The Bills are 3-3-0 against the spread this season.
- Buffalo owns one win ATS (1-1) as a 7.5-point favorite or greater this year.
- Buffalo has had two games (out of six) go over the total this season.
- Buffalo games average 46.8 total points per game this season (postseason included), 6.8 greater than the over/under for this matchup.
Patriots Betting Insights
- The Patriots have won once against the spread this year.
- The Patriots have had one game (out of six) hit the over this season.
- There have been three New England games this season with more than 40 points scored.
- The average total for Patriots games is 41.5 points, 1.5 more than this game’s over/under.
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Bills Players to Watch
- Josh Allen leads Buffalo with 1,576 yards (262.7 ypg) on 147-of-205 passing with 13 touchdowns and six interceptions this season. He also has 131 rushing yards on 22 carries while scoring three touchdowns on the ground.
- James Cook has carried the ball 75 times for a team-high 363 yards (60.5 per game) with one score. He has also caught 14 passes for 140 yards.
- Stefon Diggs has hauled in 49 catches for 620 yards (103.3 yards per game) to lead the team this season. He’s found the end zone five times as a receiver.
- Gabriel Davis has hauled in 21 receptions totaling 341 yards, finding the end zone four times as a receiver this campaign.
- Leonard Floyd leads the team with 6.5 sacks, and also has 4.0 TFL and 14 tackles.
- Terrel Bernard is the team’s leading tackler this year. He’s collected 57 tackles, 5.0 TFL, 2.0 sacks, and two interceptions.
- Micah Hyde has picked off a team-high two passes. He also has 28 tackles and two passes defended to his name.
Patriots Players to Watch
- Mac Jones has racked up 1,208 yards on 64.2% passing while tossing five touchdown passes with seven interceptions this season.
- Rhamondre Stevenson has run for 234 yards on 78 carries this year while scoring two times on the ground. He’s also added 17 catches, totaling 111 yards.
- Ezekiel Elliott has racked up 193 yards (on 49 attempts) with one touchdown.
- Kendrick Bourne has hauled in 307 receiving yards on 28 receptions to pace his squad this season while scoring two touchdowns as a receiver.
- Hunter Henry has caught 18 passes and compiled 183 receiving yards (30.5 per game) with two touchdowns.
- Mike Gesicki’s 20 targets have resulted in 15 catches for 144 yards.
- Jahlani Tavai leads the team with 1.0 sack, and also has 2.0 TFL, 37 tackles, and one interception.
- Ja’Whaun Bentley, New England’s top tackler, has 40 tackles, 3.0 TFL, and 1.0 sack this year.
- Tavai has picked off a team-leading one pass. He also has 37 tackles, 2.0 TFL, 1.0 sack, and two passes defended to his name.
How to Bet on Bills vs Patriots
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