Reds vs. Pirates Prediction: MLB Betting Lines, Stats and Picks – September 22, 2023

Written By PlayPicks Staff on September 22, 2023

The Cincinnati Reds (79-75) host the Pittsburgh Pirates (72-81) to open a three-game series at Great American Ball Park, with first pitch at 6:40 PM ET on Friday. The Reds are coming off a series defeat to the Twins, and the Pirates a series win over the Cubs.

The favored Reds (-156 on the moneyline) play at home against the Pirates (+130). The over/under for this game is 9.5.

The betting facts in the article below reference odds valid as of September 22, 2023 at 7:12 PM ET. Ready to bet? Click here to get the best DraftKings Sportsbook deposit bonus!

Reds vs Pirates Betting Lines

Favorite Favorite Moneyline Underdog Moneyline Total
Reds -156 +130 9.5

Reds Betting Insights

  • The Reds have won 22, or 57.9%, of the 38 games they’ve played as favorites this season.
  • Cincinnati has entered seven games this season favored by -156 or more and is 4-3 in those contests.
  • Bookmakers have implied with the moneyline set for this matchup that the Reds have a 60.9% chance to win.
  • So far this season, Cincinnati and its opponents have hit the over in 74 of 154 games with a total.
  • The Reds have an ATS record of 89-65-0 in 154 games with a spread this season.

Reds Last 10 Games Trend

Stat Avg/Total
Record 6-4
Runs Per Game 4.1
HR 13
ERA 4.25
K/9 9.6

Pirates Betting Insights

  • The Pirates have come away with 52 wins in the 121 contests they have been listed as the underdogs in this season.
  • This season, Pittsburgh has been victorious 29 times in 63 chances when named as an underdog of at least +130 or longer on the moneyline.
  • Oddsmakers have implied with the moneyline set for this matchup that the Pirates have a 43.5% chance of pulling out a win.
  • Pittsburgh and its opponents have gone over in 82 of its 153 games with a total set by sportsbooks this season.
  • The Pirates have posted a record of 77-76-0 against the spread this season.

Pirates Last 10 Games Trend

Stat Avg/Total
Record 6-4
Runs Per Game 4.9
HR 11
ERA 5.46
K/9 7.4

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Reds Probable Pitcher – Andrew Abbott

  • Abbott and his team are 12-7-0 ATS this season when he starts.
  • The left-hander gave up two earned runs and allowed six hits in 3 2/3 innings pitched against the New York Mets on Saturday.
  • Abbott has 13 starts of five or more innings this season in 19 chances. He averages 5.4 innings per outing.
  • In 19 appearances this season, he has finished five without allowing an earned run.
  • Abbott’s team has been victorious in 62.5% of the games he’s started as the moneyline favorite with a record of 5-3.
  • In games Abbott has started, his team is 14-5.
  • In games Abbott has started this season, the teams are 6-13-0 at hitting the over.

Reds Relief Pitchers

Name Relief App. IP Ks ERA Holds Saves
Ian Gibaut 67 71.1 66 3.15 23 2
Alexis Diaz 65 64.2 84 2.51 1 37
Buck Farmer 65 71.1 65 3.91 10 3
Sam Moll 64 58.1 65 3.24 9 1
Lucas Sims 60 56 69 3.38 22 3

Pirates Probable Pitcher – Andre Jackson

  • The Pirates are sending Jackson (1-3) to the mound to make his sixth start of the season. He is 1-3 with a 5.40 ERA and 49 strikeouts over 55 2/3 innings pitched.
  • His last appearance was out of the bullpen on Sunday when the righty tossed 4 1/3 innings against the New York Yankees, surrendering two earned runs while allowing three hits.
  • Jackson has two starts this campaign where he pitched five or more innings.
  • In five of his 16 total appearances this season he has not given up an earned run.
  • The Pirates were named the moneyline underdog for two Jackson starts this season — they lost both.
  • Jackson’s team has won one of his five starts.
  • Jackson has started five games with a total set by bookmakers this season. The teams have combined to go over the run total in two of them.

Pirates Relief Pitchers

Name Relief App. IP Ks ERA Holds Saves
David Bednar 61 64 74 2.11 0 36
Colin Holderman 57 56 58 3.86 27 2
Jose Hernandez 44 46.1 58 4.47 5 0
Ryan Borucki 32 36.1 31 2.72 7 0
Carmen Mlodzinski 29 31.2 30 1.99 8 0

Reds Hitting Trends

  • The Reds have hit two or more dingers in 51 games this season, and are 36-15 in those outings.
  • Cincinnati is 30-9 in games this season when it has had five or more extra-base hits.
  • The team is 70-29 in the games this season it has racked up at least eight hits.
  • Cincinnati has a 71-14 record in games this season when it put up five or more runs.
  • The Reds have drawn five or more walks in 46 games this season, and are 24-22 in those contests.

Pirates Hitting Trends

  • They are 29-9 this season when they hit two or more home runs in a game.
  • Pittsburgh has won 25 of its 31 games with five or more extra-base hits this season.
  • They have won 52 of the 75 games in which they’ve collected eight or more hits this season.
  • Pittsburgh has a 46-12 record this season when scoring five or more runs in a game.
  • They have won 22 of their 43 games this season in which they’ve drawn more than four free passes.

Reds vs. Pirates Prediction

Moneyline Pick: Reds (-156)
Over/Under Pick: Under (9.5)

Predictions are calculated by a data-driven algorithm derived from offensive performance metrics and probable starting pitchers.

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