Cardinals Vs Cubs: MLB Betting Lines, Stats And Predictions – May 22, 2021

Written By PlayPicks Staff on May 22, 2021

The St. Louis Cardinals (25-19) are set to take on the Chicago Cubs (23-21) on Saturday at 7:15 PM ET, airing on FOX. The Cardinals are listed as -115 favorites by bookmakers, while the underdog Cubs have -103 odds. St. Louis’ Miles Mikolas gets the start, and he’ll go against Chicago’s Adbert Alzolay.

The betting insights and predictions in this article reflect betting data from DraftKings as of May 22, 2021, 2:00 AM ET. See table below for current betting odds and CLICK HERE to place a bet at DraftKings.

Cardinals vs Cubs Betting Lines

Cardinals Betting Insights

  • The Cardinals have won 17, or 68%, of the 25 games they’ve played as favorites this season.
  • St. Louis has a record of 14-4, a 77.8% win rate, when favored by -115 or more by sportsbooks this season.
  • The Cardinals have a 51.3% chance to win this game based on the implied probability of the moneyline.
  • In their last 10 games with a total, the Cardinals and their opponents are 5-4-1 when it comes to hitting the over.

Cardinals Last 10 Games Trend

Stat Avg/Total
Record 5-5
Runs Per Game 3.7
HR 11
ERA 3.99
K/9 7.3

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Cubs Betting Insights

  • The Cubs have come away with 10 wins in the 21 contests they have been listed as the underdogs in this season.
  • Chicago has a win-loss record of 9-11 when favored by -103 or worse by sportsbooks this year.
  • Oddsmakers have implied with the moneyline set for this matchup that the Cubs have a 48.7% chance of pulling out a win.
  • In their last 10 matchups with a total posted by sportsbooks, the Cubs and their foes are 3-6-1 when it comes to hitting the over.

Cubs Last 10 Games Trend

Stat Avg/Total
Record 6-4
Runs Per Game 5.3
HR 13
ERA 2.79
K/9 8.9

Cubs Probable Pitcher – Adbert Alzolay

  • Alzolay makes the start for the Cubs, his eighth of the season. He is 2-3 with a 4.62 ERA and 39 strikeouts in 37 innings pitched.
  • The righty last appeared in relief on Wednesday, when he threw 2/3 innings against the Nationals while giving up hits.
  • In seven games this season, the 26-year-old has put up an ERA of 4.62, with 9.5 strikeouts per nine innings. Opponents are batting .195 against him.
  • Alzolay has put together six starts this season where he pitched five or more innings.
  • The Cubs are 2-3 in Alzolay’s five starts this season that they were the moneyline underdog.
  • Pitchers reflected above are based on projections as of May 22, 2021 at 2:10 AM ET and may not be the pitchers at game time.

Cardinals Hitting Splits

Split Record
Overall 25-19
Home 14-9
Road 11-10
vs LHP (Starters) 5-3
vs RHP (Starters) 20-16
Day Games 10-7
Night Games 15-12

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Cardinals Probable Pitcher – Miles Mikolas

  • Mikolas gets the nod for the Cardinals and will make his first start of the season.
  • The 32-year-old right-hander will make his season debut.
  • The Cubs ranks ninth in MLB with 210 runs scored this season. They have a .242 batting average this campaign with 54 home runs (12th in the league).
  • The right-hander did not appear in a game when his team was the moneyline favorite last season.
  • Pitchers reflected above are based on projections as of May 22, 2021 at 2:10 AM ET and may not be the pitchers at game time.

Cubs Hitting Splits

Split Record
Overall 23-21
Home 16-9
Road 7-12
vs LHP (Starters) 11-3
vs RHP (Starters) 12-18
Day Games 2-3
Night Games 21-18

Cardinals Hitting Stats

  • The Cardinals average 1.2 home runs per game to rank 12th in MLB action with 54 total home runs .
  • The Cardinals have hit two or more home runs in 16 games this season, and are 12-4 in those contests.
  • St. Louis has hit 11 home runs over the last 10 games.
  • Nolan Arenado leads St. Louis in home runs (10) and runs batted in (31) this season while batting .298.
  • Dylan Carlson has 44 hits and an OBP of .379 to go with a slugging percentage of .424 this season.

Cubs Hitting Stats

  • The Cubs’ 54 home runs rank 12th in Major League Baseball.
  • They are 9-3 this season when they hit two or more home runs in a game.
  • Over the last 10 games, Chicago has hit 13 home runs.
  • Kris Bryant leads the Cubs with 10 home runs.
  • Anthony Rizzo is batting .265 with nine doubles, two triples, five home runs and 24 walks.

Game Prediction

Moneyline Pick: Cubs (-103)

Over/Under Pick: Over (8.5)

Predictions are calculated by a data-driven algorithm derived from offensive performance metrics and probable starting pitchers.

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