Reds Vs Brewers: MLB Betting Lines, Stats And Predictions – May 22, 2021

Written By PlayPicks Staff on May 22, 2021

Coming off of a three-homer game last time out, Jesse Winker leads the Cincinnati Reds (20-23) into action as -139 favorites against the Milwaukee Brewers (21-23). Action gets underway from Great American Ball Park at 4:10 PM ET on Saturday, live on BSOH. Sonny Gray starts for Cincinnati while Milwaukee will counter with Brett Anderson.

The betting insights and predictions in this article reflect betting data from DraftKings as of May 22, 2021, 2:00 AM ET. See table below for current betting odds and CLICK HERE to place a bet at DraftKings.

Reds vs Brewers Betting Lines

Reds Betting Insights

  • This season, the Reds have won 14 out of the 28 games, or 50%, in which they’ve been favored.
  • Cincinnati has a record of 8-7, a 53.3% win rate, when favored by -139 or more by oddsmakers this season.
  • Bookmakers have implied with the moneyline set for this matchup that the Reds have a 55.9% chance to win.
  • In their last 10 games with a total, the Reds and their opponents are 6-3-1 when it comes to hitting the over.

Reds Last 10 Games Trend

Stat Avg/Total
Record 4-6
Runs Per Game 5
HR 16
ERA 6.07
K/9 10.5

Click here to get the best DraftKings Sportsbook deposit bonus!

Brewers Betting Insights

  • The Brewers have come away with eight wins in the 15 contests they have been listed as the underdogs in this season.
  • Milwaukee has a mark of 4-4 in contests where oddsmakers favor them by +118 or worse on the moneyline.
  • The moneyline set for this matchup implies the Brewers have a 44.1% chance of coming away with a victory in the contest.
  • In their last 10 games with an over/under, the Brewers and their opponents have combined to clear the total four times.

Brewers Last 10 Games Trend

Stat Avg/Total
Record 3-7
Runs Per Game 2.9
HR 6
ERA 4.40
K/9 10.1

Brewers Probable Pitcher – Brett Anderson

  • Anderson (2-3 with a 4.50 ERA and 14 strikeouts in 24 innings pitched) makes the start for the Brewers, his seventh of the season.
  • The left-hander last appeared on Saturday against the Braves, when he threw 3 2/3 innings, allowing four earned runs while giving up eight hits.
  • The 33-year-old has an ERA of 4.50, with 5.2 strikeouts per nine innings in six games this season. Opponents are batting .292 against him.
  • Anderson enters this matchup with three outings of five or more innings pitched this campaign.
  • The Brewers have a 2-3 record in Anderson’s five starts this season when they were the underdog on the moneyline.
  • Pitchers reflected above are based on projections as of May 22, 2021 at 2:13 AM ET and may not be the pitchers at game time.

Reds Hitting Splits

Split Record
Overall 20-23
Home 11-11
Road 9-12
vs LHP (Starters) 3-2
vs RHP (Starters) 17-21
Day Games 7-7
Night Games 13-16

Click here to get the best DraftKings Sportsbook deposit bonus!

Reds Probable Pitcher – Sonny Gray

  • Gray (0-3) will take to the mound for the Reds and make his seventh start of the season.
  • The right-hander gave up three earned runs in five innings pitched on Monday in his last outing, a matchup with the Giants.
  • The 31-year-old has an ERA of 3.86, a 3 strikeout-to-walk ratio and a WHIP of 1.420 in six games this season.
  • In six starts this season, Gray has lasted five or more innings three times, with an average of 5.2 innings per appearance.
  • His team has won 75% of his starts when they are favored on the moneyline (3-1).
  • Pitchers reflected above are based on projections as of May 22, 2021 at 2:13 AM ET and may not be the pitchers at game time.

Brewers Hitting Splits

Split Record
Overall 21-23
Home 10-12
Road 11-11
vs LHP (Starters) 2-6
vs RHP (Starters) 19-17
Day Games 5-7
Night Games 16-16

Reds Hitting Stats

  • The Reds rank second-best in baseball with 63 total home runs.
  • The Reds have a 12-7 record this season in games when they hit at least two home runs.
  • Cincinnati has 16 home runs during the last 10 games.
  • Nicholas Castellanos leads Cincinnati in home runs this season with 11 while driving in 27 runs.
  • Winker leads Cincinnati in homers with 11 while also batting a team-best .356 this season.

Brewers Hitting Stats

  • The Brewers rank 19th in Major League Baseball with 46 home runs.
  • They have averaged 1.2 home runs per game in their 22 road contests this season.
  • Milwaukee has hit six home runs over the last 10 games.
  • Avisail Garcia has hit a team-best six home runs.
  • Omar Narvaez is batting .352 to lead his team.

Game Prediction

Moneyline Pick: Brewers (+118)

Over/Under Pick: Over (8.5)

Predictions are calculated by a data-driven algorithm derived from offensive performance metrics and probable starting pitchers.

Powered By Data Skrive using data from

PlayPicks Staff Avatar
Written by
PlayPicks Staff

PlayPicks staff has years of sports betting and DFS knowledge and we share all of that with you for free daily.

View all posts by PlayPicks Staff
Privacy Policy