DraftKings NFL DFS Picks, Predictions And Lineup Strategy For Week 6

Posted By Nate Weitzer on October 14, 2020 - Last Updated on October 15, 2020

The 2020-21 NFL season is in full swing and there are huge Week 6 DFS contests being offered on DraftKings with big prize money up for grabs.

In this weekly column, we will identify the best plays, values, and tournament options for your NFL DFS lineups. We’ll also offer the best “fades” at each position, indicating which players to avoid when building your lineups.

Keep in mind that some of the plays offered are better for “Cash” games, i.e. 50/50, H2H, and Double-Up formats that require a more conservative approach. Some plays are recommended for GPP (Guaranteed Prize Pool) tournaments where it’s necessary to take more risk in the hopes of separating from a large field. Those GPP plays can also be ideal for Best Ball formats where players with higher upside are valuable.

For those interested in the DFS Single-Game Slate contests, here’s a quick recap:

In the “Showdown” mode on DraftKings, there are five utility spots and a “Captain” slot, who receives 1.5x multiplier for all DK points accrued. Pricing differs for players when selected in the Captain spot versus the FLEX spots, with all players required to fit under a $50k salary cap. All options are in play from QBs, RBs and WRs, to kickers and D/ST from each team.

Keep an eye on injury news right up until kickoff since things can change quickly in the NFL. Please note any player listed as questionable may see limited action or not suit up at all if he doesn’t respond well in warm-ups.


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Play-Action: $3 entry, $1.4M guaranteed – $100,000 to 1st!
Slant: $9 entry, $500k guaranteed – $50,000 to 1st!

Top NFL DFS DraftKings Plays for Week 6


Best Play: Aaron Rodgers ($7.5k)

The Packers will likely install a very pass-heavy game script against a Bucs team that ranks second in DVOA rush defense and yields a league-low 2.7 YPC. With Rodgers sporting the highest total QBR in the league, Green Bay averages the most PPG (38) this season and should get Davante Adams (hamstring) back after their bye week. This game has a 54-point total and Tom Brady should keep pace to force more volume from Rodgers.

Value Play: Ryan Fitzpatrick ($5.9k)

Since he struggled in Week 1 at New England, Fitzpatrick has completed 71.4% of his passes at 8.62 yards per attempt. He went for 288 yards and 3 TDs in last year’s home game against a Jets secondary that has become far worse without safety Jamal Adams. The Jets rank 31st in DVOA pass defense and ninth in rush defense, while the Dolphins are 11th in DVOA pass offense and 23rd in rush offense. So Fitz will be called upon to put points up against his former team.

GPP Play: Matthew Stafford ($6.3k)

Stafford only threw for 206 yards in Week 4, but still exceeded value with 3 TDs before the Lions collapsed late against the Saints. He could have another efficient day as the Lions come out of their bye to face the Jaguars 32nd-ranked pass defense. The Jags are sixth in points per red zone drive (5.64), so Stafford could be forced into a negative game script on the road. With top WR Kenny Golladay (hamstring) healthier and the Jags struggling defense further diminished by injuries, Stafford has a strong chance to top 300 yards passing.  

Fade: Deshaun Watson ($7.0k)

The Texans received a short-term lift after firing Bill O’Brien and Watson had a solid game against the lowly Jaguars. Yet the Titans seemed to rekindle their defensive prowess after 2 weeks off and throttled MVP candidate Josh Allen on Tuesday. Tennessee was far more vulnerable against the run prior to their break and Texans interim HC Romeo Crenel is committed to the run game. Also concerning for Watson’s opportunities is the fact that the Titans posted a league-high 54.84% run-play rate last week.

Running Back

Best Play: Alexander Mattison ($7.2k)

Dalvin Cook (groin) has not yet been ruled out for Week 6, but the Vikings would be wise to rest their lead back with their bye week coming in Week 7. Mattison stepped in on Sunday night with 112 yards on 20 carries (5.6 YPC) against a Seattle team that came into the game ranked fifth in DVOA rush defense. He’s averaging 4.7 YPC over 2 seasons and would be the bell cow for a team that owns a league-high 54.29% run-play rate over their last 3 outings. He has fantastic TD potential for a Vikings team that leads the NFL in points per red zone trip (6.23) and draws a cupcake matchup against Atlanta.

Value Play: Devonta Freeman ($4.9k)

Now that Freeman is up to speed with the Giants playbook, he’s operating as their clear-cut lead back with 34 touches translating to 155 scrimmage yards and a TD over his last 2 outings. The Giants (-2.5) are actually favored this week against a dysfunctional Washington team that is stronger against the pass than it is against the run. Freeman has played on 54.4% of offensive snaps in close losses over the last 2 weeks and could thrive if the Giants experience positive game script.

GPP Play: Philip Lindsay ($4.3k)

Lindsay was close to returning from a toe injury last Sunday and should be a full go now that the Broncos tilt at New England is pushed back to Week 6. He could see a significant uptick in usage if Melvin Gordon is suspended or disciplined for committing a DUI on Tuesday night. Regardless, Lindsay is in play for GPPs because the coaching staff will have to switch things up to keep pace with the Patriots. New England’s run defense has not been reliable after losing several key LBs this offseason and Lindsay has a relentless motor that allows him to churn out yards.  

Fade: James Conner ($7.1k)

The Browns defense has been fantastic since their Week 1 drubbing in Baltimore. Cleveland ranks 11th in DVOA rush defense with a defensive line that ranks second in Open Field tackling and allows the seventh-fewest RB yards (3.7) per carry according to Football Outsiders. Conner saved his fantasy day with a 25-yard run and a 1-yard TD plunge against the similarly stingy Eagles, but there are no guarantees he produces in an AFC North slugfest with the Steelers (-3.5) only slightly favored. 


Wide Receiver

Best Play: Davante Adams ($8.0k)

Adams hasn’t played since departing a Week 2 win, but he’s practicing in full ahead of a showdown at Tampa. Under DC Todd Bowles, the Bucs have played “funnel defense,” shutting down the run game and leaving their CBs on an island to allow huge games from opposing No. 1 WRs. Adams has drawn 28.2% of targets and 20% of red zone targets when he’s been on the field this season and Rodgers will look towards him even more with Allen Lazard (abdomen) out. 

Value Play: Chase Claypool ($5.2k)

We’re listing Claypool as a value rather than a GPP play because the public should be all over him following his 4 TD game last week. While he’s unlikely to go off again, the rookie out of Notre Dame should have a solid game against Cleveland’s 18th-ranked pass defense. The Browns placed CB Greedy Williams (shoulder) on I.R. and may have to use top CB Denzel Ward on JuJu Smith-Schuster. Ben Roethlisberger clearly loves Claypool, who has played on over 70% of offensive snaps with Diontae Johnson (toe/back) injured over Pittsburgh’s last 2 games.

GPP Play: Travis Fulgham ($4.4k)

With the Eagles WR corps banged up per usual, Fulgham emerged as the go-to-option for Carson Wentz and caught 10 of 13 targets for 152 yards and a TD against Pittsburgh’s elite defense. He’ll draw an even tougher test this week against CB Marlon Humphrey and the Ravens, but volume alone keeps Fulgham in GPP consideration. The Eagles are 27th in run-play rate (36.39%) this season and will quickly abandon the run if/when the Ravens front seven shuts down their 25th-ranked rushing attack. 

Fade: Marquise Brown ($6.5k)

The Eagles secondary was embarrassed by Claypool and the Steelers last week and should rectify some of those issues ahead of Sunday’s home game. Darius Slay has done well in coverage and could shadow “Hollywood” considering how often Lamar Jackson looks towards his fastest target. Brown is only drawing 5% of red zone targets and would need a big play to hit. 

Tight End

Best Play: Jonnu Smith ($5.2k)

The Titans were firing on all cylinders after their double bye week and Jonnu Smith continued his breakout season with a 5-40-2TD line against the Bills. He ranks fifth among TEs with a 20.6% target share and second in yards per route run (2.74) and separation per target (2.65) this season. With Corey Davis and Adam Humphries both inactive due to COVID-19, Smith is in line for even more consistent usage.

Value Play: Austin Hooper ($3.9k)

Hooper has really ramped things up after a slow start with the Browns, securing 10 of 17 targets for 91 yards and a TD over his last 2 outings. He doesn’t have tremendous upside in the Browns run-heavy offense, but is a solid play in PPR formats against a Steelers team that forces checkdowns over the middle of the field. If Pittsburgh sells out against the run in the red zone, look for Hooper to leak out for a TD off a play-action pass.

GPP Play: Robert Tonyan ($5.1k)

The Packers have few receiving options of note to pair with Rodgers, so Tonyan is a quality play in any format if you’re stacking Green Bay’s offense. As mentioned, Tampa’s scheme forces opposing teams to pass and is most exploitable down the seams. Tonyan is thriving on those looks from Rodgers and he’s essentially the Packers 1B receiver with Lazard out. 

Fade: Zach Ertz ($5.0k)

Somehow, Ertz has become less involved in the Eagles passing attack with Dallas Goedert (ankle) on I.R. He’s unlikely to have much success against Baltimore’s seventh-ranked pass defense and his upside is quite limited considering he ranks 36th among TEs at 7.2 yards per reception. 


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Nate Weitzer

Nate Weitzer is a successful DFS player at DraftKings and FanDuel with numerous tournament wins in NBA and NFL contests. He's been writing about DFS for several years, specializing in NBA picks and advice while continuing to build his bankroll across the daily fantasy industry. When he's not playing DFS, Weitzer is often covering high school sports in the greater Boston area for outlets such as The Boston Globe, or playing basketball himself. Follow Nate on Twitter @Nweitzer7.

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