The UFC moves to a smaller octagon for the second event at Apex Arena in Las Vegas this Saturday. All 12 preliminary fights for UFC 250 will stream live on ESPN and ESPN+ and the main card will be on ESPN+ Pay-Per-View.

The main event Saturday pits women’s dual champion Amanda Nunes against challenger Felicia Spencer. It is a huge mismatch on paper with Nunes sporting -670 odds and Spencer listed as a +475 underdog at DraftKings Sportsbook.

DraftKings is once again offering several huge DFS contests this Saturday, led by the $2.5M MMA Millionaire contest. For a $25 entry fee, users get a crack at the first $1M first prize in the history of MMA DFS. At, PlayPicks we’re once again providing our top DFS plays to help you build your DFS lineups.

There is also a healthy betting market for UFC 250 at US sportsbooks like DraftKings Sportsbook and FanDuel Sportsbook and this advice can be relevant for placing bets on the event.

In this column, we will identify the top DFS plays to consider for Cash and GPP formats for the June 6 contests at DraftKings. We also highlight sleepers and values to consider.

Keep in mind the betting lines may shift prior to the fight and news may break regarding how prepared each fighter is for their respective bout, many of which were scheduled on relatively short notice.

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UFC 250 Top DFS Plays

Amanda Nunes ($9,400)

There should be no shying away from the consensus best female fighter in MMA right now. Nunes (19-4) has successful defended her featherweight title five times and should make it six against Felicia Spencer. The Canadian Spencer (8-1) is a submission artist with two first-round victories over her last 3 fights, but she could be the fighter going down early in this matchup.

Nunes packs incredible pop with her punches and Spencer has absorbed a whopping 6.27 significant strikes per minute in those 3 UFC bouts. Nunes has defended takedowns at an 80% rate and will be well prepared for Spencer trying to get her to the ground. It took Nunes just 51 seconds to knock out Cris Cyborg in 2018 and Cyborg landed 122 strikes on Spencer to earn a U-DEC last July.

Charles Byrd ($8,800)

After dropping consecutive fights in the light heavyweight division, Byrd drops down to middleweight to take on Maki Pitolo. The 29-year-old Pitolo has earned 9 of his 12 MMA wins via stoppage and dropped his last UFC bout with the unanimous decision going to Callan Potter.

Pitolo (12-5) is giving up 15 pounds to the 185-pound Byrd and is unlikely to pound him into submission. Rather, Byrd (10-6) should deal the punishment with ample scoring given the fact he averages 2.52 takedowns per 15 minutes and lands 3.86 significant strikes per minute. Pitolo has not defended takedowns well throughout his short UFC career and he could get outmaneuvered by a bigger, more experienced fighter.

Chase Hooper ($8,500)

While he weighs in at 145 pounds, Chase Hooper doesn’t fight like your typical featherweight. The 6-foot-1 southpaw delivers punishment (5.16 strikes landed per minute) and grapples with the best of them (3.8 submissions per 15 minutes), leading to a sparkling 9-0-1 MMA record with 7 of those victories coming via stoppage.

Hooper is coming off two first-round victories and faces struggling jiu-jitsu specialist Alexander Caceres (15-12), who has dropped 4 of his last 6 fights. Caceres is not a tremendous threat to deliver a knockout and he absorbs 2.86 significant strikes per minute. He’s also three inches shorter and 11 years older than Hooper. Hooper (-180) is a good bet at reasonable odds at DK Sportsbook and a great DFS play for any format.


UFC 250 Top DFS Value Plays

Cory Sandhagen ($8,000)

The undercard features a bantamweight contender fight between Sandhagen and Aljamain Sterling (18-3) that could provide excellent value while going the distance. Sandhagen (-106) is only a slight underdog with Sterling (-118) also getting good odds at DK Sportsbook. Sterling’s fights last 12:42 on average and Sandhagen has won his last two bouts by decision.

Even if he loses by decision, Sandhagen (12-1) should score well given the fact he lands 7.14 significant strikes per minute. Sterling is a great defensive fighter (absorbs just 1.91 strikes per minute), but so is Sandhagen (absorbs 1.24 strikes per minute). Sandhagen has four consecutive fights and has a 4-inch reach advantage on Sterling, making him an excellent Cash play on this slate.

Gerald Meerschaert ($7,800)

Coming off two wins and a questionable loss to Eryk Anders, Meerschaert appears to be a bit under priced in this spot. The 33-year-old middleweight is getting even money (+100) at DK Sportsbook against Ian Heinsch (-125), who has dropped consecutive bouts via unanimous decision.

The 5-foot-11 Heinsch tends to go the distance with an average fight time of 12:43, while 29 of Meerschaert’s 31 wins have gone inside the distance. This could be a cat-and-mouse game in which Meerschaert tries to get to the mat and earn a submission, but either way the southpaw has an advantage with his 6-foot-1 frame and a 77-inch reach.

UFC 250 betting picks