The No. 1 squad in the AFC East, the Buffalo Bills (4-1), clashes with the AFC South-leading Tennessee Titans (3-2) in Week 6. The Titans ( on the moneyline to win) take to their home field on October 18, 2021 at 8:15 PM ET on ESPN against the Bills ( ). A point total of points has been set for the matchup.
The betting insights and predictions in this article reflect betting data from DraftKings as of October 18, 2021, 7:48 PM ET. See the table below for current betting odds and CLICK HERE to bet at DraftKings Sportsbook.
Bills Vs Titans Odds
|ATS pick||Over/Under pick|
|Titans (+6)||Under (53.5)|
Predictions are calculated by a data-driven algorithm (raw power score) that ranks head-to-head matchup results within a closed network of games. Prediction confidence is determined by the delta between each team’s raw power score.
Team Stat Rankings
|Off. Points per Game (Rank)||34.4 (6)||26.4 (19)|
|Def. Points per Game (Rank)||12.8 (1)||26.0 (13)|
|Off. Yards per Play (Rank)||5.9 (9)||5.3 (22)|
|Def. Yards per Play (Rank)||4.3 (1)||6.2 (27)|
|Turnovers Allowed (Rank)||4 (1)||7 (14)|
|Turnovers Forced (Rank)||15 (1)||4 (27)|
Bills Betting Insights
- Buffalo is 5-1-0 against the spread this year.
- As a 6-point favorite or greater, the Bills have two wins ATS (2-1).
- Two Buffalo games (out of six) have hit the over this year.
- Buffalo’s games have had more than 53.5 points scored on three occasions this year.
- The over/under for this game is 53.5 points, 4.4 more than the average point total for Bills games this season.
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Titans Betting Insights
- Tennessee has beaten the spread three times in five games.
- The Titans have covered every time (1-0) as a 6-point favorite or more this season.
- Tennessee has played five games this season, and three of them have gone over the total.
- Tennessee’s games have gone over 53.5 points scored twice this season.
- Games involving the Titans this year have averaged 49.6 points per game, a 3.9-point differential when compared to the over/under for this contest.
Bills Players to Watch
- Josh Allen leads Buffalo with 1,370 yards (274.0 ypg) on 114-of-183 passing with 12 touchdowns and two interceptions this season. He also has 188 rushing yards on 35 carries while scoring two touchdowns on the ground.
- Devin Singletary has carried the ball 55 times for a team-high 284 yards on the ground and has found the end zone one time as a runner.
- Stefon Diggs’ team-high 374 yards as a receiver have come on 28 catches (out of 47 targets) with one touchdown.
- Emmanuel Sanders has caught 19 passes for 322 yards (64.4 yards per game) and four touchdowns this year.
- Dawson Knox’s 18 grabs have turned into 261 yards and five touchdowns.
- Gregory Rousseau paces the team with 3.0 sacks, and also has 4.0 TFL, 18 tackles, and one interception.
- Tremaine Edmunds, Buffalo’s tackle leader, has 30 tackles, 2.0 TFL, and one interception this year.
- Micah Hyde has picked off a team-leading three passes. He also has 21 tackles, 2.0 TFL, 1.0 sack, and five passes defended to his name.
Titans Players to Watch
- Ryan Tannehill has been a dual threat to lead Tennessee in both passing and rushing. He has 1,251 passing yards (250.2 per game) while completing 63.6% of his passes. He’s thrown six touchdown passes and three interceptions this season. On the ground, he’s compiled 130 yards (26.0 ypg) on 17 carries with one rushing touchdown.
- Derrick Henry has run for 640 yards on 142 carries so far this year while scoring seven times on the ground. He’s also added 14 catches, totaling 125 yards.
- Julio Jones has totaled 12 catches this season and his team-high yardage total sits at 204 (40.8 yards per game). He’s been targeted 18 times and has .
- Chester Rogers has put together a 179-yard season so far with one touchdown. He’s caught 13 passes on 20 targets.
- Jeremy McNichols’ 17 grabs (on 23 targets) have netted him 160 yards (32.0 ypg) and one touchdown.
- Harold Landry paces the team with 4.5 sacks, and also has 6.0 TFL and 28 tackles.
- David Long is the team’s tackle leader this year. He’s picked up 29 tackles and 3.0 TFL.
- Kevin Byard leads the team with two interceptions, while also collecting 27 tackles and six passes defended.
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